Summary
Evening blue light exposure and lower wrist temperature are sensitive actigraphy markers associated with higher BMI, particularly in carriers of the MTNR1B rs10830963 G-allele, suggesting genetic susceptibility to circadian light disruption should inform lighting recommendations. Novel indices for nocturnal blue light excess (NEIbl) and daylight deficit (DDIbl) may serve as practical tools for assessing metabolic health risks linked to lighting environments.
Key Findings
- Higher BMI was significantly associated with nocturnal blue light exposure (NEIbl) in carriers of the MTNR1B rs10830963 G-allele, but not in non-carriers.
- Lower wrist temperature and higher evening blue light exposure were the most sensitive actigraphy markers associated with BMI among multiple light and activity measures.
- Higher leptin levels were associated with larger wake-after-sleep onset (WASO), smaller 24h activity amplitude, and earlier phase of the activity rhythm.
- Higher cortisol was associated with earlier M10 onset of blue light exposure and a greater Daylight Deficit Index of blue light (DDIbl).
- Sex-, age-, and population-dependent differences were found in blue light exposure and wrist temperature indices, but no differences were observed in sleep characteristics.
Categories
Sleep & Circadian Health: Study examines how light exposure patterns and circadian rhythm markers relate to metabolic health outcomes in an Arctic population.
The Science of Light: Introduces novel blue light exposure indices (NEIbl and DDIbl) as sensitive actigraphy markers, and links these to melatonin receptor polymorphism (MTNR1B rs10830963).
Author(s)
D Gubin, K Danilenko, O Stefani, S Kolomeichuk
Publication Year
2023
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