Summary
The paper discusses the synaptic connectivity within the suprachiasmatic nucleus (SCN), the central circadian pacemaker in vertebrates, and how it receives photic information through melanopsin-expressing retinal ganglion cells (mRGCs) to synchronize circadian rhythms with environmental light cycles.
Categories
Cognitive function and memory: The paper discusses the role of the suprachiasmatic nucleus (SCN) in regulating circadian rhythms, which are crucial for cognitive function and memory.
Hormone regulation: The paper explores how the SCN, through its network of synaptic connections, regulates the circadian clock, which is key to hormone regulation.
Phototherapy: The paper discusses how the SCN receives photic information through melanopsin-expressing retinal ganglion cells (mRGCs), which is relevant to phototherapy as it involves the use of light to regulate circadian rhythms.
Lighting Design Considerations: The paper's findings on how the SCN receives and processes light information can inform lighting design considerations, particularly in creating environments that support natural circadian rhythms.
Well-being: The paper's exploration of the SCN's role in regulating circadian rhythms is relevant to well-being, as disruptions in these rhythms can negatively impact physical and mental health.
Author(s)
H Calligaro, A Shoghi, X Chen, KY Kim, HL Yu, B Khov
Publication Year
2023
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Hormone regulation
- Phototransduction by retinal ganglion cells that set the circadian clock
- The impact of light from computer monitors on melatonin levels in college students
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- Effects of artificial dawn and morning blue light on daytime cognitive performance, well-being, cortisol and melatonin levels
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Phototherapy
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- Lux vs. wavelength in light treatment of Seasonal Affective Disorder
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Lighting Design Considerations
- Color appearance models
- Melanopsin-positive intrinsically photosensitive retinal ganglion cells: from form to function
- Acute alerting effects of light: A systematic literature review
- Form and function of the M4 cell, an intrinsically photosensitive retinal ganglion cell type contributing to geniculocortical vision
- Melanopsin and rod–cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
Well-being
- Acute alerting effects of light: A systematic literature review
- Effects of artificial dawn and morning blue light on daytime cognitive performance, well-being, cortisol and melatonin levels
- Can light make us bright? Effects of light on cognition and sleep
- Light pollution, circadian photoreception, and melatonin in vertebrates
- Kruithof's rule revisited using LED illumination