Summary
This thesis investigates the transcriptional and post-translational mechanisms regulating circadian rhythms in Drosophila, providing foundational understanding of how molecular clocks are maintained. While focused on basic science in a model organism, insights into clock gene regulation have downstream implications for understanding human circadian disruption and potential therapeutic targets for lighting-based interventions.
Categories
The Science of Light: Examines the molecular mechanisms underlying circadian clock function, including transcriptional and post-translational regulation relevant to circadian photobiology.
Sleep & Circadian Health: Investigates the endogenous molecular mechanisms that generate 24-hour circadian rhythms in behavioral and physiological processes.
Author(s)
Y Xue
Publication Year
2019
Related Publications
The Science of Light
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Melanopsin is required for non-image-forming photic responses in blind mice
Sleep & Circadian Health
- Phototransduction by retinal ganglion cells that set the circadian clock
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- The twoāprocess model of sleep regulation: a reappraisal
- Melanopsin is required for non-image-forming photic responses in blind mice
- Strange vision: ganglion cells as circadian photoreceptors