Summary
This paper discusses the use of light to potentiate the antidepressant response in a treatment-resistant model of depression, focusing on the role of light sensitive melanopsin retinal ganglion cells (ipRGCs) and the serotonergic system.
Categories
Depression: The paper discusses the use of light therapy in treating various forms of depression and explores the neurobiological mechanisms by which light potentiates the antidepressant response.
Cognitive function and memory: The paper mentions that aberrant light cycles and disrupted circadian rhythmicity can impair cognition.
Mood regulation: The paper discusses the role of ipRGCs in mood regulation induced by light and the effect of light on mood.
Phototherapy: The paper explores the use of light therapy in treating depression and potentiating the antidepressant response.
Hormone regulation: The paper discusses the role of the serotonergic system in mediating the antidepressant effect of light.
Author(s)
S Delcourte, R Rovera, HM Cooper
Publication Year
2019
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Depression
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- Nocturnal light exposure impairs affective responses in a wavelength-dependent manner
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Cognitive function and memory
- Phototransduction by retinal ganglion cells that set the circadian clock
- The two‐process model of sleep regulation: a reappraisal
- Strange vision: ganglion cells as circadian photoreceptors
- Information processing in the primate retina: circuitry and coding
- Melanopsin-positive intrinsically photosensitive retinal ganglion cells: from form to function
Mood regulation
- Effects of artificial dawn and morning blue light on daytime cognitive performance, well-being, cortisol and melatonin levels
- Nocturnal light exposure impairs affective responses in a wavelength-dependent manner
- The role of the circadian clock in animal models of mood disorders.
- Signalling by melanopsin (OPN4) expressing photosensitive retinal ganglion cells
- Early electronic screen exposure and autistic-like symptoms
Phototherapy
- Phototransduction by retinal ganglion cells that set the circadian clock
- Strange vision: ganglion cells as circadian photoreceptors
- Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice
- Lux vs. wavelength in light treatment of Seasonal Affective Disorder
- Short‐wavelength enrichment of polychromatic light enhances human melatonin suppression potency
Hormone regulation
- Phototransduction by retinal ganglion cells that set the circadian clock
- The impact of light from computer monitors on melatonin levels in college students
- Circadian rhythms–from genes to physiology and disease
- Effects of artificial dawn and morning blue light on daytime cognitive performance, well-being, cortisol and melatonin levels
- Light pollution, circadian photoreception, and melatonin in vertebrates