Summary
This study explores how the deubiquitinating enzyme USP2 contributes to circadian rhythm regulation through protein ubiquitination and proteasomal degradation pathways. While primarily mechanistic in nature, understanding these molecular clock components may inform future therapeutic targets for circadian disruption and its downstream effects on health and behavior.
Categories
Sleep & Circadian Health: Investigates the role of USP2 deubiquitinating enzyme in circadian rhythm regulation at the molecular level.
The Science of Light: Examines post-translational protein modification mechanisms underlying circadian clock function relevant to photobiological research.
Author(s)
K Stojkovic
Publication Year
2013
Related Publications
Sleep & Circadian Health
- Phototransduction by retinal ganglion cells that set the circadian clock
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- The twoāprocess model of sleep regulation: a reappraisal
- Melanopsin is required for non-image-forming photic responses in blind mice
- Strange vision: ganglion cells as circadian photoreceptors
The Science of Light
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Melanopsin is required for non-image-forming photic responses in blind mice