Summary
This thesis investigates the role of the Nogo-A protein in the maturation and plasticity of the mouse visual system, with reference to ipRGCs and their projections to circadian clock structures. Understanding the developmental biology of ipRGCs has implications for how light-sensing capacity matures and may inform approaches to lighting design for populations with developing or compromised visual systems.
Categories
The Science of Light: Discusses intrinsically photosensitive retinal ganglion cells (ipRGCs) and their role in circadian clock regulation and visual system maturation.
Eye Health & Vision: Examines retinal ganglion cell biology and visual system plasticity, relevant to understanding photoreceptor development and function.
Author(s)
A Guzik-Kornacka
Publication Year
2014
Related Publications
The Science of Light
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Melanopsin is required for non-image-forming photic responses in blind mice
Eye Health & Vision
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa
- Melanopsin and rod–cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
- Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types
- Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm