Summary
This review examines the role of nerve growth factor (NGF) and related neurotrophins (particularly BDNF) in synaptic plasticity and neuronal health under pathological conditions, including ocular application contexts. While primarily neuroscientific in focus, the findings on neurotrophin-mediated neuroprotection have indirect relevance to retinal health and the preservation of light-sensitive neurons.
Categories
Eye Health & Vision: The paper discusses ocularly applied NGF and its effects on neurons, with implications for retinal and ocular neurotrophic pathways.
Author(s)
P Rosso
Publication Year
2018
Related Publications
Eye Health & Vision
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa
- Melanopsin and rod–cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
- Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types
- Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm