Summary
This dissertation investigates retinal changes in three mouse models of neuronal ceroid lipofuscinosis (CLN1, CLN3, CLN6 knockouts), a group of inherited neurodegenerative disorders. The findings are relevant to understanding photoreceptor and retinal degeneration pathways, though direct lighting design applications are limited.
Categories
Eye Health & Vision: Examines retinal phenotypes in mouse models of neuronal ceroid lipofuscinosis, a condition involving retinal degeneration.
Author(s)
C Dahlmann
Publication Year
2013
Related Publications
Eye Health & Vision
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa
- Melanopsin and rod–cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
- Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types
- Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm