Summary
The paper discusses the relationship between circadian disruption and psychiatric disorders, particularly major depressive disorder, and how rapid-acting antidepressants and sleep deprivation therapy can improve symptoms by affecting clock gene expression and initiating synaptic plasticity.
Categories
Depression: The paper discusses the strong association between circadian disruption and major depressive disorder, and how rapid-acting antidepressants and sleep deprivation therapy can improve symptoms.
Sleep and insomnia: The paper discusses how sleep deprivation therapy can improve symptoms of depression within 24 hours, and how disruptions in sleep are common in depressed patients.
Cognitive function and memory: The paper discusses how the circadian clock participates in the control of diverse brain functions, including memory formation.
Psychiatric Disorders: The paper discusses the strong association between circadian disruption and psychiatric disorders, particularly major depressive disorder.
Hormone regulation: The paper discusses how circadian abnormalities associated with major depressive disorder include dysregulated rhythms of hormonal secretions.
Author(s)
S Sato, B Bunney, L Mendoza-Viveros
Publication Year
2022
Number of Citations
29
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