Summary
This thesis describes the development of a portable fundus camera (EyeFundusScope) enhanced with pupillometry capabilities for multimodal screening of diabetic retinopathy and glaucoma in underserved areas. The device's illumination system was designed with eye safety in mind, including theoretical light hazard calculations, making it relevant for safe clinical and field-based ophthalmic screening.
Key Findings
- Experimental tests confirmed the optical and mechanical design met pupillometry performance goals for glaucoma screening.
- Theoretical light hazard calculations confirmed the illumination system is safe for human eyes, with plans for future experimental safety standard compliance testing.
- The device enables multimodal acquisition combining retinal fundus imaging and pupillometry in a single portable prototype.
Categories
Eye Health & Vision: Paper focuses on optical design of a portable screening device for diabetic retinopathy and glaucoma, both leading causes of blindness.
The Science of Light: Includes pupillometry via pupillary light reflex measurement and light hazard safety calculations for illumination systems used in retinal imaging.
Author(s)
ML Santos
Publication Year
2019
Related Publications
Eye Health & Vision
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa
- Melanopsin and rod–cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
- Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types
- Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm
The Science of Light
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Melanopsin is required for non-image-forming photic responses in blind mice