Summary
This dissertation investigates optic nerve regeneration in adult mice with a focus on intrinsically photosensitive retinal ganglion cells (ipRGCs), characterizing how these cells regrow axons and reinnervate targets. Understanding ipRGC regeneration has practical implications for restoring light-mediated functions, including circadian photoentrainment and the pupillary light reflex, following optic nerve injury.
Categories
The Science of Light: The paper investigates intrinsically photosensitive retinal ganglion cells (ipRGCs) and their role in optic nerve regeneration, directly relevant to photoreceptor biology.
Eye Health & Vision: The research characterizes axonal growth and target reinnervation in retinal ganglion cells, with implications for retinal and optic nerve health.
Author(s)
BJ Yungher
Publication Year
2015
Related Publications
The Science of Light
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Eye Health & Vision
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- Melanopsin and rod–cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
- Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types
- Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm