Summary
This review examines the role of Notch signalling and the endocytic adaptor protein Numb in mammalian retinal neurogenesis and cell fate determination. While primarily basic science, understanding retinal development mechanisms has indirect relevance to conditions affecting photoreceptors and retinal health.
Categories
Eye Health & Vision: Examines retinal neurogenesis and cell fate determination in the mammalian retina, relevant to understanding photoreceptor development and retinal cell biology.
Author(s)
MC BĂ©langer
Publication Year
2018
Related Publications
Eye Health & Vision
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa
- Melanopsin and rod–cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
- Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types
- Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm