Summary
This thesis examines the biology of melanopsin-containing ipRGCs, which are the primary photoreceptors driving non-visual light responses such as circadian entrainment and the pupillary light reflex. The author proposes future studies using selective marking techniques to better characterize ipRGC populations, which could improve understanding of how lighting design influences circadian and visual health.
Categories
The Science of Light: Thesis focused on melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs) and their photoreceptor biology.
Eye Health & Vision: Research investigates retinal ganglion cell populations relevant to non-visual light responses and potential selective marking of ipRGCs.
Author(s)
M Loftin
Publication Year
2024
Related Publications
The Science of Light
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Melanopsin is required for non-image-forming photic responses in blind mice
Eye Health & Vision
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa
- Melanopsin and rod–cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
- Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types
- Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm