Summary
The paper discusses the progress and potential of using induced pluripotent stem cells (iPSCs) to generate distinct retinal cell populations and develop cell replacement therapies, with a focus on the protocols, culture conditions, and techniques employed in differentiating retinal neurons from iPSCs.
Categories
Eye health: The paper discusses the use of iPSCs to generate distinct retinal cell populations, which could potentially be used in cell replacement therapies for various retinal degenerative diseases.
Aging: The paper mentions age-related macular degeneration (AMD) as one of the retinal degenerative diseases that could potentially be treated using iPSC-derived retinal cells.
Education and learning: The paper provides a comprehensive overview of the protocols, culture conditions, and techniques employed in differentiating retinal neurons from iPSCs, serving as an educational resource for researchers and clinicians in the field.
Author(s)
NK Wong, SP Yip, CL Huang
Publication Year
2023
Related Publications
Eye health
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Strange vision: ganglion cells as circadian photoreceptors
- Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa
Aging
- Light therapy and Alzheimer's disease and related dementia: past, present, and future
- Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice
- Melanopsin-expressing intrinsically photosensitive retinal ganglion cells in retinal disease
- Neuroprotective strategies for retinal ganglion cell degeneration: current status and challenges ahead
- Combinatorial effects of alpha-and gamma-protocadherins on neuronal survival and dendritic self-avoidance
Education and learning
- Color appearance models
- Genetic dissection of retinal inputs to brainstem nuclei controlling image stabilization
- The role of the circadian system in the etiology and pathophysiology of ADHD: time to redefine ADHD?
- How to report light exposure in human chronobiology and sleep research experiments
- Simulation-aided occupant-centric building design: A critical review of tools, methods, and applications