Summary
This thesis describes the development of a LED-based device and software interface (MATLAB GUI) to measure visual perception thresholds and perform pupillometry under scotopic and photopic conditions, adapted for hospital use. The device is intended to evaluate photoreceptor functionality in patients with retinitis pigmentosa and reduced visual fields, offering a clinical tool for assessing residual vision.
Key Findings
- A protocol was established based on five reviewed articles, with the Park et al. and Kawasaki et al. models selected as most suitable for measuring visual thresholds.
- Four tests were implemented: scotopic vision threshold, photopic vision threshold, scotopic pupillometry, and photopic pupillometry, with results saved via a custom MATLAB GUI.
- An integrating sphere prototype was designed to house the LEDs and meet the measurement protocol requirements in a hospital environment for retinitis pigmentosa patients.
Categories
Eye Health & Vision: The device is designed to measure visual perception thresholds in patients with retinitis pigmentosa, assessing photoreceptor functionality under scotopic and photopic conditions.
The Science of Light: The work involves LED-based light stimulus control and pupillometry under both scotopic and photopic conditions, directly relevant to photoreceptor biology and visual threshold measurement.
Author(s)
S Loscos Fernandez
Publication Year
2014
Related Publications
Eye Health & Vision
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa
- Melanopsin and rod–cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
- Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types
- Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm
The Science of Light
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Melanopsin is required for non-image-forming photic responses in blind mice