Summary
The paper discusses the synaptic connectivity within the suprachiasmatic nucleus (SCN) of the hypothalamus in the vertebrate brain, focusing on the inputs from melanopsin-expressing retinal ganglion cells (mRGC) and how they contribute to the regulation of the circadian clock.
Categories
Cognitive function and memory: The paper explores the synaptic connections within the SCN, a part of the brain that plays a crucial role in the regulation of circadian rhythms, which are important for cognitive function and memory.
Sleep and insomnia: The study's focus on the SCN, which regulates circadian rhythms, is relevant to sleep and insomnia as disruptions in these rhythms can lead to sleep disorders.
Hormone regulation: The paper discusses the role of the SCN in regulating circadian rhythms, which involves the release of various hormones.
Lighting Design Considerations: The study examines how the SCN receives photic information from mRGCs, which could have implications for lighting design that takes into account the impact of light on circadian rhythms.
Aging: The paper mentions that the findings could provide a framework to understand the age-dependent deterioration of circadian organization.
Author(s)
H Calligaro, A Shoghi, X Chen, KY Kim, YH Liu, B Khov
Publication Year
2022
Related Publications
Cognitive function and memory
- Phototransduction by retinal ganglion cells that set the circadian clock
- The twoāprocess model of sleep regulation: a reappraisal
- Strange vision: ganglion cells as circadian photoreceptors
- Information processing in the primate retina: circuitry and coding
- Melanopsin-positive intrinsically photosensitive retinal ganglion cells: from form to function
Sleep and insomnia
- The twoāprocess model of sleep regulation: a reappraisal
- Strange vision: ganglion cells as circadian photoreceptors
- Melanopsin-positive intrinsically photosensitive retinal ganglion cells: from form to function
- Functional and morphological differences among intrinsically photosensitive retinal ganglion cells
- The impact of light from computer monitors on melatonin levels in college students
Hormone regulation
- Phototransduction by retinal ganglion cells that set the circadian clock
- The impact of light from computer monitors on melatonin levels in college students
- Circadian rhythmsāfrom genes to physiology and disease
- Effects of artificial dawn and morning blue light on daytime cognitive performance, well-being, cortisol and melatonin levels
- Light pollution, circadian photoreception, and melatonin in vertebrates
Lighting Design Considerations
- Color appearance models
- Melanopsin-positive intrinsically photosensitive retinal ganglion cells: from form to function
- Acute alerting effects of light: A systematic literature review
- Form and function of the M4 cell, an intrinsically photosensitive retinal ganglion cell type contributing to geniculocortical vision
- Melanopsin and rodācone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
Aging
- Light therapy and Alzheimer's disease and related dementia: past, present, and future
- Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice
- Melanopsin-expressing intrinsically photosensitive retinal ganglion cells in retinal disease
- Neuroprotective strategies for retinal ganglion cell degeneration: current status and challenges ahead
- Combinatorial effects of alpha-and gamma-protocadherins on neuronal survival and dendritic self-avoidance