Targeting Trends
Summary:
This paper discusses the role of cholinergic neurons in the nucleus accumbens and their involvement in schizophrenic pathology.
Categories
- Psychiatric Disorders: The paper discusses the role of cholinergic neurons in the nucleus accumbens and their involvement in schizophrenic pathology, suggesting that a reduction in these neurons may contribute to the emergence of schizophrenic symptoms.
- Cognitive function and memory: The paper discusses how the reduction of cholinergic neurons can impair performance in a T-maze task, a measurement of working memory, and can reduce in vivo activation of dopamine release in the prefrontal cortex, which correlates with cognitive impairments.
Author(s)
D Higgins
Publication Year:
2013
Number of Citations:
0