Summary
This thesis investigates how immediate early transcription factors regulate peripheral circadian clocks, shedding light on the molecular mechanisms by which organisms synchronize internal timing with environmental cues. Understanding these pathways has implications for designing lighting interventions that more effectively entrain circadian rhythms in shift workers, patients, and other populations with disrupted clocks.
Categories
Sleep & Circadian Health: Investigates molecular mechanisms of peripheral circadian clock regulation, relevant to understanding entrainment and circadian rhythm synchronization.
The Science of Light: Examines immediate early transcription factors as mediators of circadian clock resetting, including light-driven signaling pathways.
Author(s)
KY Hui
Publication Year
2015
Related Publications
Sleep & Circadian Health
- Phototransduction by retinal ganglion cells that set the circadian clock
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- The twoāprocess model of sleep regulation: a reappraisal
- Melanopsin is required for non-image-forming photic responses in blind mice
- Strange vision: ganglion cells as circadian photoreceptors
The Science of Light
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Melanopsin is required for non-image-forming photic responses in blind mice