Summary
The paper investigates the alterations of visual circuits in a mouse model of Alzheimer's disease, revealing that Aβ accumulation and neurodegeneration occurred in the retina and retinorecipient regions of early and late stages of the disease.
Categories
Alzheimer's disease: The paper uses a mouse model of Alzheimer's disease to study the alterations in visual circuits, demonstrating that Aβ accumulation and neurodegeneration occur in the retina and retinorecipient regions in both early and late stages of the disease.
Cognitive function and memory: The paper discusses how the accumulation of Aβ peptides, a causative factor in Alzheimer's disease, can provoke neurodegeneration and synaptic loss in the brain, leading to cognitive decline.
Eye health: The paper investigates the impact of Alzheimer's disease on the retina and retinorecipient areas, revealing damage to visual functions and alterations in the visual pathways.
Author(s)
Y Nam, S Kim, J Kim, HS Hoe, M Moon
Publication Year
2022
Number of Citations
1
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