Summary
This paper covers the biological mechanisms of the internal clock, including how intrinsically photosensitive retinal ganglion cells (ipRGCs) connect to the suprachiasmatic nucleus (SCN) to regulate circadian rhythms and stress hormones. Understanding these pathways has practical implications for lighting design aimed at reducing jet lag and supporting healthy circadian entrainment.
Categories
Sleep & Circadian Health: Discusses jet lag, circadian rhythms, and the SCN's role in light entrainment.
The Science of Light: Describes ipRGCs and their direct neural connections to the SCN as photoreceptors for circadian entrainment.
Author(s)
VH Oster
Related Publications
Sleep & Circadian Health
- Phototransduction by retinal ganglion cells that set the circadian clock
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- The two‐process model of sleep regulation: a reappraisal
- Melanopsin is required for non-image-forming photic responses in blind mice
- Strange vision: ganglion cells as circadian photoreceptors
The Science of Light
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Melanopsin is required for non-image-forming photic responses in blind mice