Summary
This doctoral research examines how modern lifestyle factors — light pollution, shift work, and transmeridian travel — disrupt circadian alignment in rodent models, and investigates melatonin's potential to restore circadian function (chronopotentiation). Findings from animal models of chronodisruption can inform lighting design strategies and melatonin-based interventions aimed at mitigating circadian misalignment in shift workers and light-polluted environments.
Categories
Sleep & Circadian Health: Investigates circadian system functioning under physiological and pathological chronodisruption models, including melatonin's role in chronopotentiation.
Shift Work & Staff Wellbeing: Examines how shift work and light pollution contribute to circadian misalignment in rodent models.
The Science of Light: Studies the mechanisms of circadian disruption caused by light pollution and its effects on internal temporal organization.
Author(s)
B Baño Otálora
Publication Year
2013
Related Publications
Sleep & Circadian Health
- Phototransduction by retinal ganglion cells that set the circadian clock
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- The two‐process model of sleep regulation: a reappraisal
- Melanopsin is required for non-image-forming photic responses in blind mice
- Strange vision: ganglion cells as circadian photoreceptors
Shift Work & Staff Wellbeing
- Off the clock: from circadian disruption to metabolic disease
- Endocrine regulation of circadian physiology
- Working against the biological clock: a review for the Occupational Physician
- Shiftwork and light at night negatively impact molecular and endocrine timekeeping in the female reproductive axis in humans and rodents
- Circadian Rhythms Disrupted by Light at Night and Mistimed Food Intake Alter Hormonal Rhythms and Metabolism
The Science of Light
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Melanopsin is required for non-image-forming photic responses in blind mice