Summary
This paper examines retinal phototoxicity with reference to the third photosensitive cell type in the retina — intrinsically photosensitive retinal ganglion cells (ipRGCs) containing melanopsin — which are relevant to understanding how light exposure can cause retinal damage. For lighting designers and healthcare professionals, understanding the phototoxic thresholds and spectral sensitivity of retinal cells is critical for developing safe lighting systems, particularly in clinical and high-intensity environments.
Categories
Eye Health & Vision: Discusses retinal phototoxicity and photosensitive cells in the retina, directly relevant to eye health and potential light-induced damage.
The Science of Light: Covers melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs), fundamental to understanding photoreceptor biology and light sensitivity.
Author(s)
I Sande Pérez
Publication Year
2015
Related Publications
Eye Health & Vision
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa
- Melanopsin and rod–cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
- Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types
- Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm
The Science of Light
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Melanopsin is required for non-image-forming photic responses in blind mice