Summary
This study investigates how prenatal valproic acid exposure disrupts circadian organization and clock-gene expression, with implications for understanding circadian dysfunction in autism spectrum disorders. The findings highlight the role of ipRGCs in SCN entrainment, suggesting that lighting interventions targeting the circadian system may have therapeutic relevance for ASD populations.
Categories
The Science of Light: Discusses ipRGCs and their role in SCN innervation relevant to circadian photoentrainment mechanisms.
Sleep & Circadian Health: Examines effects of prenatal valproic acid on circadian organization and clock-gene expression relevant to ASD circadian disruption.
Neonatal Care: Investigates prenatal factors affecting circadian development with implications for neurodevelopmental conditions like autism spectrum disorders.
Author(s)
S Ferraro
Publication Year
2021
Related Publications
The Science of Light
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Sleep & Circadian Health
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- Melanopsin is required for non-image-forming photic responses in blind mice
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Neonatal Care
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- No loss of melanopsin-expressing ganglion cells detected during postnatal development of the mouse retina
- The retinal basis of light aversion in neonatal mice
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- Mechanisms of Cardiovascular Changes of Phototherapy in Newborns with Hyperbilirubinemia.