Summary
This paper examines how ipRGCs distributed across the retina respond to illuminance in the plane of the pupil, with gaze aversion behavior influencing effective light exposure. Understanding these mechanisms is important for designing lighting systems that effectively drive circadian and non-visual responses without causing discomfort.
Categories
The Science of Light: Discusses ipRGC distribution and its role in driving non-visual light responses, relevant to understanding melanopic sensitivity and pupillary light reflex.
Eye Health & Vision: Addresses gaze aversion and pupillary responses in the context of retinal illuminance, with implications for visual comfort and safe lighting design.
Author(s)
L Guan, J Unwin
Publication Year
2016
Related Publications
The Science of Light
- Phototransduction by retinal ganglion cells that set the circadian clock
- Color appearance models
- The mammalian circadian timing system: organization and coordination of central and peripheral clocks
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Melanopsin is required for non-image-forming photic responses in blind mice
Eye Health & Vision
- Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice
- Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa
- Melanopsin and rod–cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans
- Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types
- Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm