Summary
This review summarizes genomic and transcriptomic research on myopia in humans and animal models, identifying biochemical pathways involved in myopia progression. The findings have implications for early diagnosis and the development of targeted preventive or therapeutic interventions for myopia control.
Key Findings
- Review identifies altered biochemical pathways and genetic markers associated with myopia pathogenesis across human and animal model studies.
- Precision medicine approaches based on genomic and transcriptomic profiling are proposed as a framework for more effective myopia prevention and treatment, though no specific quantitative effect sizes are reported in the abstract.
Categories
Eye Health & Vision: Reviews genomic and transcriptomic mechanisms underlying myopia development, relevant to understanding and preventing visual impairment.
Author(s)
L Jiang, DX Goh, JHZ Koh, X Chan, NA Brennan
Publication Year
2023
Number of Citations
6
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