The role of the deubiquitinase USP2 in modulating behavior and circadian light response in mice
Summary:
This paper investigates the role of deubiquitinase USP2 in modulating behavior and circadian light response in mice, finding that USP2 substantially regulates animal behavior and affects circadian behaviors.
Categories
- Cognitive function and memory: The paper discusses how the absence of USP2 in mice leads to a reduction in recognition memory.
- Alertness and performance: The paper explores how USP2 affects motor coordination in mice, with mice lacking USP2 showing reduced motor coordination.
- Mood regulation: The paper finds that mice lacking USP2 show reduced anxiety-like behaviors, indicating a role for USP2 in mood regulation.
- Lighting Design Considerations: The paper investigates how USP2 modulates the light response of the circadian clock in mice, affecting early-night entrainment and entrainment to a light cue.
Author(s)
S Srikanta
Publication Year:
2023
Number of Citations:
0
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