Extensive Soma-Soma Plate-Like Contact Sites (Ephapses) Connect Suprachiasmatic Nucleus Neurons
Summary:
The paper investigates the structural basis for synchronization in the suprachiasmatic nucleus (SCN) neurons, revealing extensive soma-soma plate-like contact sites between adjacent neurons, which could account for the persistence of mutual synchronization of the cell-autonomous neuronal oscillators comprising the SCN core.
Categories
- Cognitive function and memory: The paper discusses the synchronization of SCN neurons, which are crucial for maintaining circadian rhythms and thus impact cognitive function and memory.
- Sleep and insomnia: The research focuses on the SCN, the central pacemaker for mammalian circadian rhythms, which regulates sleep cycles.
- Hormone regulation: The paper discusses the role of the SCN in driving circadian oscillations governing physiology and behavior, including hormone regulation.
- Phototherapy: The paper mentions the role of light-dark cycles in synchronizing the SCN, suggesting a potential relevance to phototherapy.
Author(s)
MÉ Czeisler, Y Shan, R Schalek, DR Berger
Publication Year:
2022
Number of Citations:
0
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